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Article

Promoter hypermethylation of tumor‐related genes in gastric intestinal metaplasia of patients with and without gastric cancer

22 Oct 2002

Abstract excerpt

Promoter hypermethylation is an alternative mechanism of gene silencing in human cancers including gastric cancer. While intestinal metaplasia (IM) is generally regarded as a precancerous lesion of the stomach, our study examines the presence of gene promoter hypermethylation in IM of patients with and without gastric cancer. We examined 31 samples of gastric cancer, 36 gastric IM (21 associated with gastric...

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Share to Cancer-related gene regulation
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Share to Helicobacter pylori-related gastroenterology studies

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PMID: 12448005
DOI: 10.1002/ijc.10783

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