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Article

Differential DNA methylation profiles in gynecological cancers and correlation with clinico-pathological data

23 Aug 2006

Abstract excerpt

BACKGROUND: Epigenetic gene silencing is one of the major causes of carcinogenesis. Its widespread occurrence in cancer genome could inactivate many cellular pathways including DNA repair, cell cycle control, apoptosis, cell adherence, and detoxification. The abnormal promoter methylation might be a potential molecular marker for cancer management. METHODS: For rapid identification of potential targets for...

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Share to Endometrial and Cervical Cancer Treatments
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PMID: 16928264
DOI: 10.1186/1471-2407-6-212

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