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Article

HLA-DPB1-COL11A2 and three additional xMHC loci are independently associated with RA in a UK cohort.

Genes and immunity - 1 Apr 2011

Orozco G, Barton A, Eyre S, Ding B, Worthington J, Ke X, Thomson W

Abstract excerpt

The aim of this study was to investigate the complex association pattern of the extended major histocompatibility complex (xMHC) region with rheumatoid arthritis (RA) susceptibility to identify effects independent of HLA-DRB1. A total of 1804 RA cases and 1474 controls were included. High-resolution HLA-DRB1 typing was performed. Subjects were genotyped for 1546 single-nucleotide polymorphisms (SNPs) using...

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Share to Arthritis, Rheumatoid
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21293383
DOI: 10.1038/gene.2010.57

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