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Article

Identification of BACH2 and RAD51B as rheumatoid arthritis susceptibility loci in a meta-analysis of genome-wide data.

Arthritis and rheumatism - 1 Dec 2013

McAllister Kate, Yarwood Annie, Bowes John, Orozco Gisela, Viatte Sebastian, Diogo Dorothée, Hocking Lynne J, Steer Sophia, Wordsworth Paul, Wilson A G, Morgan Ann W, Kremer Joel M, Pappas Dimitrios, Gregersen Peter, Klareskog Lars, Plenge Robert, Barton Anne, Greenberg Jeffrey, Worthington Jane, Eyre Stephen

Abstract excerpt

OBJECTIVE: A recent high-density fine-mapping (ImmunoChip) study of genetic associations in rheumatoid arthritis (RA) identified 14 risk loci with validated genome-wide significance, as well as a number of loci showing associations suggestive of significance (P = 5 × 10(-5) < 5 × 10(-8)), but these have yet to be replicated. The aim of this study was to determine whether these potentially significant loci are...

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Identifiers

PMID: 24022229
DOI: 10.1002/art.38183
PMCID: PMC4034583

Genes

BACH2

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