Article
Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci.
Arthritis and rheumatism - 1 Jan 2009
Vignal Charlotte, Bansal Aruna T, Balding David J, Binks Michael H, Dickson Marion C, Montgomery Doug S, Wilson Anthony G
Abstract excerpt
OBJECTIVE: The HLA-DRB1 locus within the major histocompatibility complex (MHC) at 6p21.3 has been identified as a susceptibility gene for rheumatoid arthritis (RA); however, there is increasing evidence of additional susceptibility genes in the MHC region. The aim of this study was to estimate their number and location. METHODS: A case-control study was performed involving 977 control subjects and 855 RA...
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