Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenome-wide association study of rheumatoid arthritis identifies differentially methylated loci in B cells

4 May 2017

Abstract excerpt

Epigenetic regulation of immune cell types could be critical for the development and maintenance of autoimmune diseases like rheumatoid arthritis (RA). B cells are highly relevant in RA, since patients express autoantibodies and depleting this cell type is a successful therapeutic approach. Epigenetic variation, such as DNA methylation, may mediate the pathogenic activity of B cells. In this study, we performed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Epigenetics and DNA Methylation
Share to Lymphoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28475762
DOI: 10.1093/hmg/ddx177

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenome-wide association study of rheumatoid arthritis identifies differentially methylated loci in B cellsPMID 28475762Read ↗

Differentially Methylated DNA Regions in Monozygotic Twin Pairs Discordant for Rheumatoid Arthritis: An Epigenome-Wide StudySemantic proximity Read ↗

Lymphocyte DNA methylation mediates genetic risk at shared immune-mediated disease loci.Semantic proximity Read ↗

Next-Generation Sequencing Profiles of the Methylome and Transcriptome in Peripheral Blood Mononuclear Cells of Rheumatoid ArthritisSemantic proximity Read ↗

Genome-wide DNA methylation patterns in CD4+ T cells from Chinese Han patients with rheumatoid arthritisSemantic proximity Read ↗

Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis.Semantic proximity Read ↗

Differential CpG DNA methylation in peripheral naïve CD4+ T-cells in early rheumatoid arthritis patientsSemantic proximity Read ↗

Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosusSemantic proximity Read ↗

DNA Methylation of T Lymphocytes as a Therapeutic Target: Implications for Rheumatoid Arthritis EtiologySemantic proximity Read ↗

Genetics, epigenetics and autoimmunity constitute a Bermuda triangle for the pathogenesis of rheumatoid arthritis.Semantic proximity Read ↗

Rheumatoid arthritis-relevant DNA methylation changes identified in ACPA-positive asymptomatic individuals using methylome capture sequencingSemantic proximity Read ↗

Thousands of CpGs Show DNA Methylation Differences in ACPA-Positive Individuals.Semantic proximity Read ↗

Hypomethylation of CYP 2E1 and DUSP 22 Promoters Associated With Disease Activity and Erosive Disease Among Rheumatoid Arthritis PatientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.