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Article

In vivo metabolic flux profiling with stable isotopes discriminates sites and quantifies effects of mitochondrial dysfunction in C. elegans.

Molecular genetics and metabolism - 1 Mar 2014

Vergano Samantha Schrier, Rao Meera, McCormack Shana, Ostrovsky Julian, Clarke Colleen, Preston Judith, Bennett Michael J, Yudkoff Marc, Xiao Rui, Falk Marni J

Abstract excerpt

UNLABELLED: Mitochondrial respiratory chain (RC) disease diagnosis is complicated both by an absence of biomarkers that sufficiently divulge all cases and limited capacity to quantify adverse effects across intermediary metabolism. We applied high performance liquid chromatography (HPLC) and mass...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24445252
DOI: 10.1016/j.ymgme.2013.12.011
PMCID: PMC3947636

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24445252-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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