Article
Role of interleukin-28B polymorphisms in the treatment of hepatitis C virus genotype 2 infection in Asian patients.
Hepatology (Baltimore, Md.) - 1 Jan 2011
Yu Ming-Lung, Huang Chung-Feng, Huang Jee-Fu, Chang Ning-Chia, Yang Jeng-Fu, Lin Zu-Yau, Chen Shinn-Cherng, Hsieh Ming-Yuh, Wang Liang-Yen, Chang Wen-Yu, Li Yi-Ning, Wu Mei-Shin, Dai Chia-Yen, Juo Suh-Hang Hank, Chuang Wan-Long
Abstract excerpt
UNLABELLED: Genome-wide association studies have linked single nucleotide polymorphisms (SNPs) near the interleukin-28B gene to the hepatitis C virus genotype 1 (HCV-1) response to peginterferon/ribavirin treatment. We aimed to explore the impact on the treatment outcomes of Asian HCV-2 patients. We determined rs8105790, rs8099917, rs4803219, and rs10853728 to be candidate SNPs in 482 Asian HCV-2 patients treated...
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