Article
Interleukin-28B gene non-TT allele strongly predicts treatment failure for genotype 1 infected chronic hepatitis C patients with advanced fibrosis: a case control study.
BMC infectious diseases - 26 Mar 2015
Hu Ching-Chih, Lin Chih-Lang, Chang Liang-Che, Chien Cheng-Hung, Chen Li-Wei, Liu Ching-Jung, Chien Rong-Nan
Abstract excerpt
BACKGROUND: The role of single nucleotide polymorphisms (SNPs) of interleukin (IL)-28B in predicting therapeutic response of pegylated interferon (peg-IFN) plus ribavirin (PR) for genotype 1 infected chronic hepatitis C patients with advanced fibrosis (AF) is limited. The aim of this study is to assess its role in predicting sustained virologic responses (SVR) to treatment. METHODS: Forty-two patients with biopsy...
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