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Article

Predictive value of the IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b.

Journal of hepatology - 1 Mar 2011

Kawaoka Tomokazu, Hayes C Nelson, Ohishi Waka, Ochi Hidenori, Maekawa Toshiro, Abe Hiromi, Tsuge Masataka, Mitsui Fukiko, Hiraga Nobuhiko, Imamura Michio, Takahashi Shoichi, Kubo Michaki, Tsunoda Tatsuhiko, Nakamura Yusuke, Kumada Hiromitsu, Chayama Kazuaki

Abstract excerpt

BACKGROUND & AIMS: Common IL28B locus polymorphisms (SNPs rs8099917 and rs12979860) have been reported to affect peg-interferon plus ribavirin combination therapy (PEG-RBV) for hepatitis C virus (HCV) genotype 1b, but few reports have examined their effect on other two common genotypes, 2a and 2b. METHODS: We analyzed predictive factors for sustained virological response (SVR) in a retrospective study of 719...

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Identifiers

PMID: 21112660
DOI: 10.1016/j.jhep.2010.07.032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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