Article
The predictive value of IL28B rs12979860, rs11881222 and rs8099917 polymorphisms and IP-10 in the therapeutic response of Egyptian genotype 4 patients.
Virology - 1 Sept 2013
Derbala Moutaz, Rizk Nasser M, Al-Kaabi Saad, John Anil, Sharma Manik, El-dweik Nazeeh, Yakoob Rafie, Pasic Fuad, Almohanadi Muneera, Alejji Khalid, Abdelmola Abdulatif, Butt Mohamed
Abstract excerpt
UNLABELLED: Interleukin-28B (IL28B) polymorphisms have previously been reported to be strongly associated with spontaneous and treatment-induced HCV viral clearance. AIM: To assess the impact of four different IL28B polymorphisms and their haplotype combination and interferon-c inducible protein 10 (IP-10) in response to treatment in Egyptian genotype 4 patients. METHOD: 159 HCV-genotype 4 patients were included....
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