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Article

DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines.

Genome biology - 1 Jan 2011

Bell Jordana T, Pai Athma A, Pickrell Joseph K, Gaffney Daniel J, Pique-Regi Roger, Degner Jacob F, Gilad Yoav, Pritchard Jonathan K

Abstract excerpt

BACKGROUND: DNA methylation is an essential epigenetic mechanism involved in gene regulation and disease, but little is known about the mechanisms underlying inter-individual variation in methylation profiles. Here we measured methylation levels at 22,290 CpG dinucleotides in lymphoblastoid cell lines from 77 HapMap Yoruba individuals, for which genome-wide gene expression and genotype data were also available....

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Share to DNA Methylation
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21251332
DOI: 10.1186/gb-2011-12-1-r10
PMCID: PMC3091299

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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