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Article

Regions of common inter-individual DNA methylation differences in human monocytes: genetic basis and potential function.

Epigenetics & chromatin - 26 Jul 2017

Schröder Christopher, Leitão Elsa, Wallner Stefan, Schmitz Gerd, Klein-Hitpass Ludger, Sinha Anupam, Jöckel Karl-Heinz, Heilmann-Heimbach Stefanie, Hoffmann Per, Nöthen Markus M, Steffens Michael, Ebert Peter, Rahmann Sven, Horsthemke Bernhard

Abstract excerpt

BACKGROUND: There is increasing evidence for inter-individual methylation differences at CpG dinucleotides in the human genome, but the regional extent and function of these differences have not yet been studied in detail. For identifying regions of common methylation differences, we used whole genome bisulfite sequencing data of monocytes from five donors and a novel bioinformatic strategy. RESULTS: We...

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PMID: 28747224
DOI: 10.1186/s13072-017-0144-2
PMCID: PMC5530492

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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