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Article

Alpha-Synuclein Is a Cellular Ferrireductase

10 Jan 2011

Abstract excerpt

α-synuclein (αS) is a cellular protein mostly known for the association of its aggregated forms with a variety of diseases that include Parkinson's disease and Dementia with Lewy Bodies. While the role of αS in disease is well documented there is currently no agreement on the physiological function of the normal isoform of the protein. Here we provide strong evidence that αS is a cellular ferrireductase,...

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PMID: 21249223
DOI: 10.1371/journal.pone.0015814

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