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Structural Properties of α-Synuclein in Functional and Pathological Contexts

2016-01-01

Abstract excerpt

α-synuclein (αS) is an intrinsically disordered protein that is strongly connected with Parkinson’s disease (PD) and a number of other neurodegenerative disorders, including Parkinson’s disease with dementia, dementia with Lewy bodies and multiple system amyotrophy. Fibrillar aggregates of αS have been identified as the major constituents of proteinaceous inclusions known as Lewy bodies that form inside the neuron...

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Literature Corpus work
422dcb70-dea8-5b8e-833f-50919e83f1d5
DOI
10.17863/cam.26244
Open publication

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