Article
Interactions between metals and alpha-synuclein--function or artefact?
The FEBS journal - 1 Aug 2007
Brown David R
Abstract excerpt
alpha-synuclein is one of a family of proteins whose function remains unknown. This protein has become linked to a number of neurodegenerative disease although its potential causative role in these diseases remains mysterious. In diseases such as Parkinson's disease and Lewy body dementias, alpha-synuclein becomes deposited in aggregates termed Lewy bodies. Also, some inherited forms of Parkinson's diseases are...
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