Article
Mutagenic properties of a unique abasic site in mammalian cells.
Biochemical and biophysical research communications - 14 Dec 1990
Gentil A, Renault G, Madzak C, Margot A, Cabral-Neto J B, Vasseur J J, Rayner B, Imbach J L, Sarasin A
Abstract excerpt
The mutagenic properties of a true unique abasic site located opposite a guanine residue were studied. An oligonucleotide containing a chemically-produced abasic site was inserted into a shuttle vector able to replicate both in simian cells and in bacteria. Plasmid DNA was rescued from simian cel...
Topics
- Animals
- Base Sequence
- Cells, Cultured
- Chromosome Mapping
- DNA
- Gene Frequency
- Haplorhini
- Molecular Sequence Data
- Mutation
- Plasmids