Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutagenic properties of a unique abasic site in mammalian cells.

Biochemical and biophysical research communications - 14 Dec 1990

Gentil A, Renault G, Madzak C, Margot A, Cabral-Neto J B, Vasseur J J, Rayner B, Imbach J L, Sarasin A

Abstract excerpt

The mutagenic properties of a true unique abasic site located opposite a guanine residue were studied. An oligonucleotide containing a chemically-produced abasic site was inserted into a shuttle vector able to replicate both in simian cells and in bacteria. Plasmid DNA was rescued from simian cells and screened in bacteria by differential hybridization with a labelled oligonucleotide probe. Mutations were easily...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cells, Cultured

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosome Mapping

Share to Gene Frequency

Share to Molecular Sequence Data

Share to Mutation

Share to Plasmids

Source

Identifiers

PMID: 2124487
DOI: 10.1016/s0006-291x(05)80092-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutagenic properties of a unique abasic site in mammalian cells.PMID 2124487Read ↗

Repair and mutagenic potency of 8-oxoG:A and 8-oxoG:C base pairs in mammalian cells.Semantic proximity Read ↗

Mutagenicity of a unique apurinic/apyrimidinic site in mammalian cellsSemantic proximity Read ↗

Mutation frequency and spectrum resulting from a single abasic site in a single-stranded vector.Semantic proximity Read ↗

Mutation spectra induced by replication of two vicinal oxidative DNA lesions in mammalian cells.Semantic proximity Read ↗

Difference between deoxyribose- and tetrahydrofuran-type abasic sites in the in vivo mutagenic responses in yeast.Semantic proximity Read ↗

Mutagenicity of a unique 8-oxoguanine in a human Ha-ras sequence in mammalian cells.Semantic proximity Read ↗

Mechanisms and consequences of mutation induction in mammalian cells.Semantic proximity Read ↗

Mutagenic specificity of endogenously generated abasic sites in Saccharomyces cerevisiae chromosomal DNA.Semantic proximity Read ↗

Double-stranded break can be repaired by single-stranded oligonucleotides via the ATM/ATR pathway in mammalian cells.Semantic proximity Read ↗

Endogenous DNA damage and spontaneous mutagenesis in cultured mammalian cells.Semantic proximity Read ↗

Replicative bypass of abasic site in Escherichia coli and human cells: similarities and differences.Semantic proximity Read ↗

[Molecular mechanisms of mutations induced by DNA lesions].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.