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Article

Purifying Selection in the Toll-Like Receptors of Song Sparrows Melospiza melodia.

The Journal of heredity - 27 Jun 2018

Nelson-Flower Martha J, Germain Ryan R, MacDougall-Shackleton Elizabeth A, Taylor Sabrina S, Arcese Peter

Abstract excerpt

Variation in immune gene sequences is known to influence resistance to infectious diseases and parasites, and hence survival and mate choice, across animal taxa. Toll-like receptors (TLRs) comprise one essential gene family in the vertebrate innate immune system and recognize evolutionarily conserved structures from all major microorganism classes. However, the causes and consequences of TLR variation in...

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Amino Acid Sequence
Evolution, Molecular
TLR3 gene
Heterozygote
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Selection, Genetic

Toll-Like Receptors

Source

Identifiers

PMID: 29893971
DOI: 10.1093/jhered/esy027

Genes

TLR3
TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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