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Article

Molecular evolution of bovine Toll-like receptor 2 suggests substitutions of functional relevance.

BMC evolutionary biology - 20 Oct 2008

Jann Oliver C, Werling Dirk, Chang Jung-Su, Haig David, Glass Elizabeth J

Abstract excerpt

BACKGROUND: There is accumulating evidence that polymorphism in Toll-like receptor (TLR) genes might be associated with disease resistance or susceptibility traits in livestock. Polymorphic sites affecting TLR function should exhibit signatures of positive selection, identified as a high ratio of non-synonymous to synonymous nucleotide substitutions (omega). Phylogeny based models of codon substitution based on...

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Identifiers

PMID: 18937834
DOI: 10.1186/1471-2148-8-288
PMCID: PMC2588590

Genes

TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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