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Article

BDNF: New Views of an Old Player in Traumatic Brain Injury.

The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry - 1 Oct 2024

Giesler Lauren P, Mychasiuk Richelle, Shultz Sandy R, McDonald Stuart J

Abstract excerpt

Traumatic brain injury is a common health problem affecting millions of people each year. BDNF has been investigated in the context of traumatic brain injury due to its crucial role in maintaining brain homeostasis. Val66Met is a functional single-nucleotide polymorphism that results in a valine-to-methionine amino acid substitution at codon 66 in the BDNF prodomain, which ultimately reduces secretion of BDNF....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37067029
DOI: 10.1177/10738584231164918
PMCID: PMC11423547

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

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Research trail→

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BDNF: New Views of an Old Player in Traumatic Brain Injury.PMID 37067029Read ↗

The Influence of the Val66Met Polymorphism of Brain-Derived Neurotrophic Factor on Neurological Function after Traumatic Brain Injury.Semantic proximity Read ↗

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Brain-derived neurotrophic factor (Val66Met) polymorphism does not influence recovery from a post-traumatic vegetative state: a blinded retrospective multi-centric study.Semantic proximity Read ↗

Missense Mutation of Brain Derived Neurotrophic Factor (BDNF) Alters Neurocognitive Performance in Patients with Mild Traumatic Brain Injury: A Longitudinal Study.Semantic proximity Read ↗

Variation in the BDNF gene interacts with age to predict mortality in a prospective, longitudinal cohort with severe TBI.Semantic proximity Read ↗

New Frontiers in Neurodegeneration and Regeneration Associated with Brain-Derived Neurotrophic Factor and the rs6265 Single Nucleotide Polymorphism.Semantic proximity Read ↗

Genetics of stroke recovery: BDNF val66met polymorphism in stroke recovery and its interaction with aging.Semantic proximity Read ↗

The BDNF gene Val66Met polymorphism as a modifier of psychiatric disorder susceptibility: progress and controversy.Semantic proximity Read ↗

The Met allele of the BDNF Val66Met polymorphism predicts poor outcome among survivors of aneurysmal subarachnoid hemorrhage.Semantic proximity Read ↗

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