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Article

BDNFVal66met polymorphism: a potential bridge between depression and thrombosis.

European heart journal - 7 May 2017

Amadio Patrizia, Colombo Gualtiero I, Tarantino Eva, Gianellini Sara, Ieraci Alessandro, Brioschi Maura, Banfi Cristina, Werba José P, Parolari Alessandro, Lee Francis S, Tremoli Elena, Barbieri Silvia S

Abstract excerpt

AIMS: Epidemiological studies strongly suggest a link between stress, depression, and cardiovascular diseases (CVDs); the mechanistic correlation, however, is poorly understood. A single-nucleotide polymorphism in the BDNF gene (BDNFVal66Met), associated with depression and anxiety, has been proposed as a genetic risk factor for CVD. Using a knock-in mouse carrying the BDNFVal66Met human polymorphism, which...

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Source

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Identifiers

PMID: 26705390
DOI: 10.1093/eurheartj/ehv655
PMCID: PMC6251610

Genes

BDNF
SIRT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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BDNFVal66met polymorphism: a potential bridge between depression and thrombosis.PMID 26705390Read ↗

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