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Article

Rumba and Haus3 are essential factors for the maintenance of hematopoietic stem/progenitor cells during zebrafish hematopoiesis.

Development (Cambridge, England) - 1 Feb 2011

Du Linsen, Xu Jin, Li Xiuling, Ma Ning, Liu Yanmei, Peng Jinrong, Osato Motomi, Zhang Wenqing, Wen Zilong

Abstract excerpt

The hallmark of vertebrate definitive hematopoiesis is the establishment of the hematopoietic stem/progenitor cell (HSPC) pool during embryogenesis. This process involves a defined ontogenic switching of HSPCs in successive hematopoietic compartments and is evolutionarily conserved from teleost fish to human. In zebrafish, HSPCs originate from the ventral wall of the dorsal aorta (VDA), from which they...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21228005
DOI: 10.1242/dev.054536

Genes

HAUS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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