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Article

cMyb regulates hematopoietic stem/progenitor cell mobilization during zebrafish hematopoiesis.

Blood - 13 Oct 2011

Zhang Yiyue, Jin Hao, Li Li, Qin F Xiao-Feng, Wen Zilong

Abstract excerpt

The establishment of the HSC pool in vertebrates depends not only on the formation and the propagation of these stem cells but also on their proper trafficking among the defined hematopoietic organs. However, the physiologic mechanisms that regulate HSC mobilization remain elusive. Through analysis of the zebrafish cmyb mutant cmyb(hkz3), we show that the suppression of cMyb function abrogates larval and adult...

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PMID: 21856868
DOI: 10.1182/blood-2011-03-342501

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