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Article

The homeodomain protein Meis1 is essential for definitive hematopoiesis and vascular patterning in the mouse embryo.

Developmental biology - 15 Apr 2005

Azcoitia Valeria, Aracil Miguel, Martínez-A Carlos, Torres Miguel

Abstract excerpt

Homeodomain proteins of the Meis subfamily are expressed dynamically in several organs during embryogenesis and exert potent regulatory activity through their interaction with Hox proteins and other transcription factors. Here we show that Meis1 is expressed in the hematopoietic stem cell (HSC) compartment in the fetal liver, and in the primary sites of definitive hematopoiesis, including the...

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Identifiers

PMID: 15882575
DOI: 10.1016/j.ydbio.2005.01.004

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