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Article

Processivity errors of gene expression in Escherichia coli.

Journal of molecular biology - 20 Oct 1990

Jørgensen F, Kurland C G

Abstract excerpt

Not all ribosomes that initiate translation of an mRNA sequence will successfully complete it and produce a full-length protein product. By comparing the amounts of lacZ monomer and lacZ dimer protein expressed from a plasmid in a strictly controlled assay, we calculate a dimer to monomer ratio of 0.76. We interpret this to mean that ribosomes have a 76% chance of completing the synthesis of a beta-galactosidase...

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Identifiers

PMID: 2121997
DOI: 10.1016/S0022-2836(05)80164-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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