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Article

Fetal RHD genotyping in maternal plasma at 11-13 weeks of gestation.

Fetal diagnosis and therapy - 1 Jan 2011

Akolekar Ranjit, Finning Kirstin, Kuppusamy Ramesh, Daniels Geoff, Nicolaides Kypros H

Abstract excerpt

OBJECTIVE: To examine the feasibility of fetal RHD genotyping at 11-13 weeks' gestation from analysis of circulating cell-free fetal DNA (ccffDNA) in the plasma of RhD negative pregnant women using a high-throughput robotic technique. METHODS: Stored plasma (0.5 ml) from 591 RhD negative women was used for extraction of ccffDNA by a robotic technique. Real-time quantitative polymerase chain reaction (PCR) with...

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Source

Identifiers

PMID: 21212654
DOI: 10.1159/000322959

Genes

RHD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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