Article
Effect of high throughput RHD typing of fetal DNA in maternal plasma on use of anti-RhD immunoglobulin in RhD negative pregnant women: prospective feasibility study.
BMJ (Clinical research ed.) - 12 Apr 2008
Finning Kirstin, Martin Pete, Summers Joanna, Massey Edwin, Poole Geoff, Daniels Geoff
Abstract excerpt
OBJECTIVES: To assess the feasibility of applying a high throughput method, with an automated robotic technique, for predicting fetal RhD phenotype from fetal DNA in the plasma of RhD negative pregnant women to avoid unnecessary treatment with anti-RhD immunoglobulin. DESIGN: Prospective comparison of fetal RHD genotype determined from fetal DNA in maternal plasma with the serologically determined fetal RhD...
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