Article
Host genetic susceptibility to pneumococcal and meningococcal disease: a systematic review and meta-analysis.
The Lancet. Infectious diseases - 1 Jan 2009
Brouwer Matthijs C, de Gans Jan, Heckenberg Sebastiaan G B, Zwinderman Aeilko H, van der Poll Tom, van de Beek Diederik
Abstract excerpt
Streptococcus pneumoniae and Neisseria meningitidis can cause sepsis and meningitis. Several risk factors for pneumococcal and meningococcal disease have been identified, but the cause of basic differences in susceptibility between individuals and populations is unknown. Single-nucleotide polymorphisms are thought to explain interindividual differences in susceptibility. New technologies provide the opportunity...
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