Article
Lack of association between IL-1 and IL-6 gene polymorphisms and myocardial infarction in Turkish population.
International journal of immunogenetics - 1 Jun 2011
Coker A, Arman A, Soylu O, Tezel T, Yildirim A
Abstract excerpt
Inflammation and genetics play a key role in the pathogenesis of atherosclerosis and its clinical result myocardial infarction (MI). Proinflammatory cytokines, IL-1 and IL-6, have been shown to play essential roles in developmental stages of coronary artery plaque formation. The aim of this study was to determine the association between IL-1 [IL-1RN, IL-1β (-511, +3953)], IL-6 [-174, -572, -597] gene...
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