Article
No association of interleukin-6 gene polymorphism (-174 G/C) with premature coronary artery disease in a Turkish cohort.
Coronary artery disease - 1 Aug 2007
Sekuri Cevad, Cam Fethi Sirri, Sagcan Abdi, Ercan Ertugrul, Tengiz Istemihan, Alioglu Emin, Berdeli Afig
Abstract excerpt
OBJECTIVES: Interleukin-6 (IL-6) may contribute to the inflammatory response by activating endothelial cells and stimulating the synthesis of fibrinogen. It might thus be important in the pathogenesis of inflammation associated with coronary artery disease (CAD). Several studies suggested that the -174 C allele was associated with an increased prevalence of coronary heart disease. The aim of this study was to...
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