Article
No association of interleukin-6 gene polymorphism (-174 G/C) with myocardial infarction or traditional cardiovascular risk factors.
International journal of cardiology - 1 Nov 2004
Lieb Wolfgang, Pavlik Robert, Erdmann Jeanette, Mayer Bjoern, Holmer Stephan R, Fischer Marcus, Baessler Andrea, Hengstenberg Christian, Loewel Hannelore, Doering Angela, Riegger Guenter A, Schunkert Heribert
Abstract excerpt
BACKGROUND: Recently, a polymorphism at position -174 (G>C) of the interleukin-6 (IL-6) promoter was found to be associated with an increased prevalence of myocardial infarction (MI). The aim of the present study was to further investigate the association of the IL-6 -174 G/C allele status with specific end organ damage, i.e. myocardial infarction in large population-based samples. METHODS: Individuals from two...
Topics
- Adult
- Aged
- Case-Control Studies
- Female
- Genotype
- Germany
- Heart Ventricles
- Humans
- Interleukin-6
- Male
- Middle Aged
- Myocardial Infarction
- Polymorphism, Genetic