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Article

-174G>C interleukin-6 gene polymorphism in Tunisian patients with coronary artery disease.

Annals of Saudi medicine - 1 Jan 2000

Ghazouani Lakhdar, Abboud Nesrine, Ben Hadj Khalifa Sonia, Added Faouzi, Ben Khalfallah Ali, Nsiri Brahim, Mediouni Mounira, Mahjoub Touhami

Abstract excerpt

BACKGROUND AND OBJECTIVES: A state of low-grade inflammation accompanies the pathogenesis of atherosclerotic events. Interleukin-6 (IL-6) is a pleotropic pro-inflammatory cytokine that modulates the development of acute coronary syndromes (ACSs), partly by destabilizing coronary atherosclerotic plaques. We have examined the contribution of the -174G>C IL-6 promoter variant on the risk of coronary artery disease...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21245598
DOI: 10.4103/0256-4947.75777
PMCID: PMC3101724

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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