Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Association of IL-6, TNFα and CRP Gene Polymorphisms with Coronary Artery Disease in a Tunisian Population: A Case-Control study.

Biochemical genetics - 1 Jun 2021

Grira Nedra, Lahidheb Dhaker, Lamine Oussama, Ayoub Manel, Wassaifi Souhir, Aouni Zied, Fehri Wafa, Mazigh Chakib

Abstract excerpt

Coronary artery disease is an inflammatory disease. Systemic markers of inflammation such as Interleukin-6, Tumor Necrosis Factor alpha and C-reactive protein have previously been shown to be associated with increased risk of cardiovascular events. The aim of the present study is to assess the role of variants in the IL-6 (- 174 G/C), TNFα (- 308 A/G) and CRP (+ 1059G/C) genes as susceptibility markers for CAD in...

Topics

Join the communities discussing this publication.

Aged, 80 and over
Coronary Artery Disease
Genetic Markers
Interleukin-6
Receptors, Immunologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 33527329
DOI: 10.1007/s10528-021-10035-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Association of IL-6, TNFα and CRP Gene Polymorphisms with Coronary Artery Disease in a Tunisian Population: A Case-Control study.PMID 33527329Read ↗

-174G>C interleukin-6 gene polymorphism in Tunisian patients with coronary artery disease.Semantic proximity Read ↗

TNF-alpha -308G>A and IL-6 -174G>C polymorphisms in Tunisian patients with coronary artery disease.Semantic proximity Read ↗

Genetic association of pro-inflammatory cytokine gene polymorphisms with coronary artery disease (CAD) in a North Indian population.Semantic proximity Read ↗

-308G>A and -1031T>C tumor necrosis factor gene polymorphisms in Tunisian patients with coronary artery disease.Semantic proximity Read ↗

Association between CRP and TNF-α genes Variants and Cardiovascular Heart Disease in a Mexican Population: Protocol for a Case-Control Study.Semantic proximity Read ↗

Promoter variants of TNF-α rs1800629 and IL-10 rs1800871 are independently associated with the susceptibility of coronary artery disease in north Indian.Semantic proximity Read ↗

Association of interleukin-6 gene promoter polymorphism with coronary artery disease in Pakistani families.Semantic proximity Read ↗

IL-6 gene promoter polymorphisms and risk of coronary artery disease in a Chinese population.Semantic proximity Read ↗

Interleukin 6(-174G/C) variant and its circulating levels in coronary artery disease patients and their first degree relatives.Semantic proximity Read ↗

Genetic polymorphisms of interleukin-6 gene and susceptibility to coronary artery disease in Chinese population: Evidence based on 4582 subjects.Semantic proximity Read ↗

Evaluation of the contribution of renin angiotensin system polymorphisms to the risk of coronary artery disease among Tunisians.Semantic proximity Read ↗

Association between the -2518G/A polymorphism in the monocyte chemoattractant protein-1 (MCP-1) gene and myocardial infarction in Tunisian patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.