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Article

Genetic polymorphism of interleukin-6 gene and susceptibility to acute myocardial infarction.

Coronary artery disease - 1 Aug 2011

Vakili Hosain, Ghaderian Sayyed Mohammad Hossein, Akbarzadeh Najar Reza, Tabatabaei Panah Akram Sadat, Azargashb Eznollah

Abstract excerpt

OBJECTIVES: Inflammatory processes play a pivotal role in the pathogenesis of atherosclerosis. Genes coding for cytokines such as interleukin-6 (IL-6) are candidates for predisposing to the risk of coronary artery disease. The aim of this study was to investigate whether molecular polymorphism of the IL-6 gene is involved in the predisposition to acute myocardial infarction (AMI). METHODS: Genomic DNA and...

Topics

C-Reactive Protein
Case-Control Studies
DNA Primers
Female
Genetic Predisposition to Disease
Genotype
Humans
Interleukin-6
Iran
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Myocardial Infarction

Oligonucleotide Probes

Polymorphism, Genetic

Prospective Studies

Reverse Transcriptase Polymerase Chain Reaction

Source

Identifiers

PMID: 21512395
DOI: 10.1097/MCA.0b013e328346b848

Genes

CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-21512395-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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