Article
Detecting directional selection in the presence of recent admixture in African-Americans.
Genetics - 1 Mar 2011
Lohmueller Kirk E, Bustamante Carlos D, Clark Andrew G
Abstract excerpt
We investigate the performance of tests of neutrality in admixed populations using plausible demographic models for African-American history as well as resequencing data from African and African-American populations. The analysis of both simulated and human resequencing data suggests that recent admixture does not result in an excess of false-positive results for neutrality tests based on the frequency spectrum...
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