Article
Disentangling the effects of demography and selection in human history.
Molecular biology and evolution - 1 Jan 2005
Stajich Jason E, Hahn Matthew W
Abstract excerpt
Demographic events affect all genes in a genome, whereas natural selection has only local effects. Using publicly available data from 151 loci sequenced in both European-American and African-American populations, we attempt to distinguish the effects of demography and selection. To analyze large sets of population genetic data such as this one, we introduce "Perlymorphism," a Unix-based suite of analysis tools....
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