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Article

Association of an IL-4 gene haplotype with Graves disease in children: experimental study and meta-analysis.

Human immunology - 1 Mar 2011

Lee Yann-Jinn, Huang Chi-Yu, Ting Wei-Hsin, Lee Hung-Chang, Guo Wen-Ling, Chen Wei-Fang, Lin Chiung-Ling, Liu Hsin-Fu, Lin Marie, Lo Fu-Sung

Abstract excerpt

Investigations of an association between Graves disease (GD) and the IL-4 gene have yielded conflicting results. We performed a case-control study of IL-4 gene polymorphisms possibly associated with GD, as well as a meta-analysis of other such studies. We genotyped IL-4 single nucleotide polymorphisms (SNPs) rs2243250 and rs2243289 in 220 unrelated children with GD and 904 healthy controls. No significant...

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Identifiers

PMID: 21195738
DOI: 10.1016/j.humimm.2010.12.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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