Article
Association of CTLA-4 and IL-13 gene polymorphisms with Graves' disease and ophthalmopathy in Chinese children.
Investigative ophthalmology & visual science - 1 Jun 2008
Chong Kelvin K L, Chiang Sylvia W Y, Wong Gary W K, Tam Pancy O S, Ng Tsz-Kin, Hu Yi-Jun, Yam Gary H F, Lam Dennis S C, Pang Chi-Pui
Abstract excerpt
PURPOSE: The frequency of childhood Graves' disease (GD) in Hong Kong Chinese is among the highest in the world but childhood Graves' ophthalmopathy (GO) appears to have milder clinical severity than does the adult disease. This study was conducted to investigate CTLA-4 and IL-13 polymorphisms in Chinese pediatric patients with GD and GO. METHODS: Recruited for the study were 177 childhood patients with GD (age...
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