Article
An association of interleukin-10 gene polymorphisms with Graves' disease in two Chinese populations.
Endocrine - 1 Aug 2011
Liu Nan, Lu Hao, Tao Feng, Guo Ting, Liu Changqin, Cui Bin, Ning Guang
Abstract excerpt
Graves' disease (GD) is a common autoimmune disorder with a genetic predisposition. The cytokine interleukin-10 (IL-10) has a central role in mediating inflammation, which may affect the outcome of the patients with GD. To elucidate the impact of IL-10 gene polymorphisms, we performed a two-stage case-control association study of five single-nucleotide polymorphisms (SNPs) within the IL-10 gene as well as a...
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