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Article

Genetic modifications of mouse proopiomelanocortin peptide processing.

Molecular and cellular endocrinology - 10 Apr 2011

Costa Jessica L, Forbes Stacy, Brennan Miles B, Hochgeschwender Ute

Abstract excerpt

Pro-opiomelanocortin (POMC) is a prohormone which undergoes extensive tissue and cell specific post-translational processing producing a number of active peptides with diverse biological roles ranging from control of adrenal function to pigmentation to the regulation of feeding. One approach to unraveling the complexities of the POMC system is to engineer mouse mutants which lack specific POMC peptides. We...

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Source

Identifiers

PMID: 21195130
DOI: 10.1016/j.mce.2010.12.032

Genes

POMC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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