Article
Haplotype analysis of the ARMS2/HTRA1 region in Japanese patients with typical neovascular age-related macular degeneration or polypoidal choroidal vasculopathy.
Japanese journal of ophthalmology - 1 Nov 2010
Gotoh Norimoto, Yamashiro Kenji, Nakanishi Hideo, Saito Masaaki, Iida Tomohiro, Yoshimura Nagahisa
Abstract excerpt
PURPOSE: To compare the genomic contribution of the ARMS2/HTRA1 region of chromosome 10q26 to typical neovascular age-related macular degeneration (nAMD) (also known as typical exudative AMD) and to polypoidal choroidal vasculopathy (PCV) METHODS: DNA samples were prepared from 84 patients with typical nAMD, 181 patients with PCV, and 276 control participants. All of the 18 haplotype-tagging single-nucleotide...
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