Gene-gene interaction of CFH, ARMS2, and ARMS2/HTRA1 on the risk of neovascular age-related macular degeneration and polypoidal choroidal vasculopathy in Chinese population.

doi:10.1038/eye.2015.32

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Article

Gene-gene interaction of CFH, ARMS2, and ARMS2/HTRA1 on the risk of neovascular age-related macular degeneration and polypoidal choroidal vasculopathy in Chinese population.

Eye (London, England) - 1 May 2015

Huang L, Meng Q, Zhang C, Sun Y, Bai Y, Li S, Deng X, Wang B, Yu W, Zhao M, Li X

Abstract excerpt

PURPOSE: To evaluate the association and interaction of five single-nucleotide polymorphisms (SNPs) in three genes (CFH, ARMS2, and ARMS2/HTRA1) with neovascular age-related macular degeneration (nAMD) and polypoidal choroidal vasculopathy (PCV) in Chinese population. METHODS: A total of 300 nAMD and 300 PCV patients and 301 normal subjects participated in the present study. The allelic variants of rs800292,...

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Identifiers

PMID: 25771815
DOI: 10.1038/eye.2015.32
PMCID: PMC4429281

Genes

ARMS2
CFH
HTRA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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