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Article

Genetic and functional dissection of ARMS2 in age-related macular degeneration and polypoidal choroidal vasculopathy.

PloS one - 1 Jan 2013

Cheng Yong, Huang LvZhen, Li Xiaoxin, Zhou Peng, Zeng Wotan, Zhang ChunFang

Abstract excerpt

Age-related maculopathy susceptibility 2(ARMS2) was suggested to be associated with neovascular age-related macular degeneration (nAMD) and polypoidal choroidal vasculopathy (PCV) in multiple genetic studies in Caucasians and Japanese. To date, no biological properties have been attributed to the putative protein in nAMD and PCV. The complete genes of ARMS2 and HTRA1 including all exons and the promoter region...

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Source

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Identifiers

PMID: 23326481
DOI: 10.1371/journal.pone.0053665
PMCID: PMC3541181

Genes

ARMS2
HTRA1
RPE

Variants

rs10490924

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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Genetic and functional dissection of ARMS2 in age-related macular degeneration and polypoidal choroidal vasculopathy.PMID 23326481Read ↗

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