Article
Analysis of candidate genes for age-related macular degeneration subtypes in the Japanese population.
Molecular vision - 1 Jan 2011
Tanaka Koji, Nakayama Tomohiro, Yuzawa Mitsuko, Wang Zhaoxia, Kawamura Akiyuki, Mori Ryusaburou, Nakashizuka Hiroyuki, Sato Naoyuki, Mizutani Yoshihiro
Abstract excerpt
PURPOSE: Age-related macular degeneration (AMD) is thought to be a polygenetic disease. It is divided into three subtypes; neovascular AMD (nAMD), polypoidal choroidal vasculopathy, and retinal angiomatous proliferation (RAP). These subtypes are thought to have different pathophysiological and genetic backgrounds. We aimed to investigate the relationships between single nucleotide polymorphisms (SNPs) in...
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