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Article

Three major loci involved in age-related macular degeneration are also associated with polypoidal choroidal vasculopathy.

Ophthalmology - 1 Aug 2010

Lima Luiz H, Schubert Carl, Ferrara Daniela C, Merriam Joanna E, Imamura Yutaka, Freund K Bailey, Spaide Richard F, Yannuzzi Lawrence A, Allikmets Rando

Abstract excerpt

PURPOSE: To investigate the frequency of variants in 3 major age-related macular degeneration (AMD)-associated loci in patients of European-American descent with polypoidal choroidal vasculopathy (PCV). DESIGN: Cross-sectional, case-control association study. PARTICIPANTS: Fifty-five patients with PCV, 368 patients with advanced AMD, and 368 age-matched and ethnically matched unaffected controls of...

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Source

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Identifiers

PMID: 20378180
DOI: 10.1016/j.ophtha.2009.12.018
PMCID: PMC2901561

Genes

CFH
ARMS2
CFB
HTRA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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