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Article

CFH and ARMS2 variations in age-related macular degeneration, polypoidal choroidal vasculopathy, and retinal angiomatous proliferation.

Investigative ophthalmology & visual science - 1 Nov 2010

Hayashi Hisako, Yamashiro Kenji, Gotoh Norimoto, Nakanishi Hideo, Nakata Isao, Tsujikawa Akitaka, Otani Atsushi, Saito Masaaki, Iida Tomohiro, Matsuo Keitaro, Tajima Kazuo, Yamada Ryo, Yoshimura Nagahisa

Abstract excerpt

PURPOSE: To seek an association in Japanese individuals between the CFH polymorphisms Y402H and I62V and the ARMS2 polymorphism A69S and age-related macular degeneration (AMD) or its three subtypes: typical (t)AMD, polypoidal choroidal vasculopathy (PCV), and retinal angiomatous proliferation (RAP). METHODS: The three polymorphisms were genotyped in a case-control study of 1351 control subjects and 962 patients...

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Source

Identifiers

PMID: 20574013
DOI: 10.1167/iovs.10-5554

Genes

ARMS2
CFH

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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