Article
ARMS2 (LOC387715) variants in Japanese patients with exudative age-related macular degeneration and polypoidal choroidal vasculopathy.
American journal of ophthalmology - 1 Jun 2009
Gotoh Norimoto, Nakanishi Hideo, Hayashi Hisako, Yamada Ryo, Otani Atsushi, Tsujikawa Akitaka, Yamashiro Kenji, Tamura Hiroshi, Saito Masaaki, Saito Kuniharu, Iida Tomohiro, Matsuda Fumihiko, Yoshimura Nagahisa
Abstract excerpt
PURPOSE: To determine the characteristics of the polymorphisms in the ARMS2 gene in Japanese patients with age-related macular degeneration (AMD) and those with polypoidal choroidal vasculopathy (PCV) and in healthy controls, and also to show possible associations of the polymorphisms with the disease. DESIGN: Case-control association study. METHODS: Fifty-six unrelated Japanese individuals with AMD, 55 with PCV,...
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