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Article

Differentiation of exudative age-related macular degeneration and polypoidal choroidal vasculopathy in the ARMS2/HTRA1 locus.

Investigative ophthalmology & visual science - 31 May 2012

Liang Xiao Ying, Lai Timothy Y Y, Liu David T L, Fan Alex H, Chen Li Jia, Tam Pancy O S, Chiang Sylvia W Y, Ng Tsz Kin, Lam Dennis S C, Pang Chi Pui

Abstract excerpt

PURPOSE: differentiate the associations of exudative age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV) with the ARMS2/HTRA1 locus. METHODS: The entire ARMS2 sequence was sequenced and HTRA1 rs11200638 genotyped in 568 unrelated Chinese individuals: 156 exudative AMD patients, 164 PCV patients, and 248 controls. A meta-analysis was performed to examine the effects of rs10490924 and...

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Source

Identifiers

PMID: 22491416
DOI: 10.1167/iovs.11-8135

Genes

ARMS2
HTRA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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