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Article

Segregation analysis of plasma lipoprotein(a) levels in pedigrees with molecularly defined familial hypercholesterolemia.

Genetic epidemiology - 1 Jan 1995

Friedlander Y, Leitersdorf E

Abstract excerpt

The role of genetic and environmental factors in determining the variability in plasma lipoprotein(a) [Lp(a)] levels was investigated in 220 members of 14 families with familial hypercholesterolemia (FH) whose plasma Lp(a) levels were previously reported [Leitersdorf et al. (1991) J Lipid Res 32:1513-1519]. One hundred four subjects harbored a mutant low density lipoprotein (LDL) receptor allele as confirmed by...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Alleles
Child
Child, Preschool
Female
Humans
Hyperlipoproteinemia Type II
Infant
Lipoprotein(a)

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Mutation

Receptors, LDL

Source

Identifiers

PMID: 7607414
DOI: 10.1002/gepi.1370120203

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7607414-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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