Article
Association of the HLA-DRB1 alleles with characteristic MRI features of Asian multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Nov 2008
Matsuoka T, Matsushita T, Osoegawa M, Kawano Y, Minohara M, Mihara F, Nishimura Y, Ohyagi Y, Kira J
Abstract excerpt
BACKGROUND: In Asian patients with multiple sclerosis (MS), a paucity of brain lesions and longitudinally extensive spinal cord lesions (LESCLs) extending three or more vertebral segments are characteristic findings on magnetic resonance imaging (MRI). We aimed to disclose possible factors contributing to the development of such MRI features. METHOD: Genotyping of HLA-DRB1 and -DPB1 alleles was performed in 121...
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